产品货号：
Z18841
中文名称：
IKK Alpha/CHUK抗体
英文名称：
Anti-IKK Alpha/CHUK Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IKK Alpha/CHUK Antibody |
| 指标别名 | component of inhibitor of nuclear factor kappa B kinase complex;IKBKA;IKK-alpha;IKK1;IKKA;NFKBIKA;TCF16;CHUK |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | CHUK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human IKK alpha recombinant protein (Position:V411-E745).Human IKK alpha shares 98% amino acid (aa) sequence identity with mouse IKK alpha. |
| 实际分子量 | 85KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | IKKA,also known as conserved helix-loop-helix ubiquitous kinase (CHUK) or IKBKA,is a protein kinase that in humans is encoded by the CHUK gene.It is mapped to 10q24.31.This gene encodes a member of the serine/threonine protein kinase family.The encoded protein,a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex,phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway,thereby activating the transcription factor.IKKA is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription factor.However,IKKA also has many additional cellular targets,and is thought to function independently of the NF-κB pathway to regulate epidermal differentiation. |
| Uniprot ID | O15111 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | conserved helix-loop-helix ubiquitous kinase |
| 蛋白名全称 | Inhibitor of nuclear factor kappa-B kinase subunit alpha |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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